Health & Beauty

Gateway for Cancer Research Concludes Phase I Clinical Trial Using 'Tumor Paint' in Pediatric Brain Cancer Surgery

Gateway for Cancer Research reported the completion of a Phase I clinical project led by Dr. Sarah Leary, pediatric oncologist at Seattle Children's Hospital, which used a promising new discovery called "Tumor Paint" in children undergoing brain tumor surgery.

According to a media release, Tumor Paint (known as tozuleristide or BLZ-100) is a protein-linked dye based on the discovery of tumor-binding properties from the venom of the Israeli death stalker scorpion. The re-engineered protein, which seeks and enters into cancer cells, is joined with a fluorescent molecule to create a molecular "flashlight." Administered intravenously before surgery, the "paint" lights up tumor tissue under near-infrared light.

The aim of Tumor Paint is to allow neurosurgeons to precisely target and remove cancer cells, especially when there are areas of uncertainty, while helping to preserve healthy tissue.

With an $800,000 grant from Gateway, Dr. Leary's clinical trial began in 2015 at Seattle Children's Hospital, which has the largest pediatric Brain Tumor Program and the most pediatric neurosurgeons in the Pacific Northwest.

"Gateway is proud to announce the successful completion of Dr. Leary's Phase I pediatric cancer clinical trial using Tumor Paint," said Gateway President Teresa Hall Bartels. "We are dedicated to supporting early phase trials where the need is great for research funding, and breakthroughs are so crucial to help courageous patients fight cancer."

The Gateway-supported trial at Seattle Children's Hospital enrolled and treated 28 patients between the ages of 6 months and 19 years. Tumor Paint was found to be safe with no noticeable side effects in pediatric patients undergoing neurosurgical resection of brain and spinal cord tumors. Over 80 percent of pediatric tumors evaluated were found to be fluorescent using Tumor Paint. Phase l was completed with bridge work leading to Phase ll. This work includes the development of CANVAS imaging system, supported by the Norcliffe Foundation, which is a specialized camera which attaches to the end of the microscope that provides continuous near-infrared lighting for the surgeon throughout the operation.

Dr. Leary commented, "Gateway's focus on funding research that touches patients has been essential to accelerating our work. We were able to bring what we thought was a great idea in the laboratory all the way to children with brain tumors in record time, including facilitating the first use of the CANVAS imaging device in the world as part of our pediatric brain tumor trial."

With Gateway's support, Dr. Leary is working on the next phase of the Tumor Paint study via the Pacific Pediatric Neuro Oncology Consortium (PNOC), which is to include 15 leading pediatric brain tumor research institutions in the US and Canada.

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  • Alexandra Scarborough
    Gilt and Sarah Jessica Parker Unveil SJP by Sarah Jessica Parker Bridal Collection for Spring

    Sarah Jessica Parker, in partnership with Gilt, kicked off the exclusive launch of SJP by Sarah Jessica Parker Bridal, Gilt’s first foray into bridal ready-to-wear that would have Carrie Bradshaw swooning.

    The collection includes dresses, skirts, bodysuits and other pieces, ranging in price from $295 to $2,395 and from sizes 0 to 14.

    "Collaborating with Gilt on my first bridal ready-to-wear collection was an opportunity I couldn't pass up," said Sarah Jessica Parker. "The team there is brilliant and allowed me to be imaginative and take risks as I was designing for the non-traditional bride. It has been quite fun to play around with colors, fabrics and details to create unique pieces for all kinds of brides." The collection, comprised of ten styles, is inspired by Parker's vision of a modern, non-traditional bride, and is designed to dress a woman for a variety of wedding milestone moments; from her bridal shower through her wedding reception. Styles offered are a unique mix of classic dresses and gowns, modern bodysuits, full skirts, and a jumpsuit. The color palette includes traditional bridal white, sleek black, plus pops of blush, poppy, light gray and blue.

    Designed in collaboration with Gilt, the collection was produced in New York City utilizing fabrics like cashmere and stretch crepe sourced from Spain, Italy and France.

    The pieces all feature carefully curated details like elegant bows, sophisticated cutouts, feathers, intricate embroidery and beautiful hand-stitched beading. 

    The actress and style icon is no stranger to chic bridal wear. Carrie Badshaw, famously played by Parker, took part in an elaborate bridal photo shoot in Sex and the City: The Movie. The shoot featured gowns from designers like Christian Lacroix and Lanvin. Parker famously wore a black wedding gown for her own wedding to Matthew Broderick in 1997.

    "Not only is Sarah Jessica Parker's style known around the world, her point of view is one-of-a-kind," says Tom Ott, Chief Merchant of Gilt. "Sarah Jessica brings her impeccable taste and fashion sensibility to life in this collection. We think our customers will be delighted with the offering which is stylish and well-priced in the bridal category."

    As part of the bridal launch, Gilt will also offer 15 exclusive styles from the SJP by Sarah Jessica Parker footwear line, each of which are complementary to the bridal collection. 

    To correspond with the bridal collection launch, Gilt City will present offers from some of Sarah Jessica Parker's favorite places in New York City.

    The offers were each chosen as a way to help brides plan for and celebrate the big day with highlights including, Leather Spa, Lars Nord Studio Tailoring, Mah-Ze-Dahr Bakery, among others.

    More Information:

  • Alexandra Scarborough
    Tea Forté Introduces ‘Matcha’ Collection

    Convenience meets tradition in Tea Forté’s new Ceremonial Matcha Bowl Set and the Matcha Single Steeps.

    The company said its spring harvested, shade grown, stone ground, organic matcha tea is best served in a centuries-old Japanese tea ceremony called chanoyu: a preparation technique known for its centering meditative qualities.

    "The launch of Tea Forté's Matcha collection represents our continued commitment to wellness and cultivating all the potential mental and physical health benefits of tea," says Tea Forté CEO Michael Gebrael. "In addition to our high quality Pure Matcha, we've also blended four distinct flavored Matcha varieties. Prepackaged in pouches measured out for a single serving, our Single Steeps Matcha is ideal for the office, travel, or to keep with you for a boost anytime."

    Tea Forté noted its handcrafted ceremonial tea bowl, handmade bamboo whisk and measuring ladle “encourages serene enjoyment of our premium Kosher, gluten-free and vegan matcha blends.” These include: Pure Matcha, Chocolate Matcha, Coconut Matcha, Ginger Matcha, and Chai Matcha.

    According to a release, in addition to its distinctive taste, matcha is prized for its health benefits. Steeped green tea contains only the antioxidants that can be extracted in water, while with matcha, the whole leaf is consumed.

    Available now in select stores and online at



QUICK 5 has released a year-end look at U.S. traveler behavior and trends for 2017, analyzing data to identify the most in-demand destinations, hotels, activities and more.

Among other insights, the roundup revealed:

  1. Labor Day was the busiest weekend for car rental
  2. Disney Theme Parks topped the list of things to do
  3. The average hotel stay was two nights
  4. Top destinations based on 2017 air travel included major global cities like New York, London and Bangkok
  5. Popular tourist destinations included Orlando, Cancun and Las Vegas